Obviously I spend a lot of time reading about the newest science on dietary supplemements, and occasionally I come across something that I think should be shared with everybody. A few years back a study was published that looked at the types of bacteria in the intestines of fat and thin people. We all have about a trillion little bugs in our GI tract, and most have a symbiotic relationship with you.

Anyway, the results of this study indicated that they type and population of bacteria in fat people is totally different than that of thin people, and those individuals who were obese but lost weight also shifted the types of bacteria in their gut from those found in the fat group to that of the thin group. Well, for the probiotic industry, this created a lot of buzz and speculation that probiotics may actually have an impact on your body weight.

As I said, that was a couple of months ago, but in looking at the nutritional news this morning, it looks like somebody has already attempted to make the jump. Now before reading the below excerpt, please realize that this data is just preliminary, and is probably very specific to the individual breed of bacteria that they studies. As such, you probably won’t get a similar effect running to the store to buy some yogurt, or buying a probiotic nutritional supplement. This article does however raise some questions on what impact different probiotics may have on post baby weight in the future.

Here is the article as it appeared in NutraIngredients

Probiotics may help women regain their figures after pregnancy

Probiotic supplements during the first trimester of pregnancy may help women lose weight after the infant’s birth, say new findings presented today at the European Congress on Obesity.

Finnish researchers report that supplements containing Lactobacillus and Bifidobacterium were associated with less central obesity, defined as a body mass index (BMI) of 30 or more or a waist circumference over 80 centimetres.

“The results of our study, the first to demonstrate the impact of probiotics-supplemented dietary counselling on adiposity, were encouraging,” said researcher Kirsi Laitinen from the University of Turku in Finland. “The women who got the probiotics fared best. One year after childbirth, they had the lowest levels of central obesity as well as the lowest body fat percentage.”

“Central obesity, where overall obesity is combined with a particularly fat belly, is considered especially unhealthy,” added Laitinen. “We found it in 25 per cent of the women who had received the probiotics along with dietary counseling, compared with 43 per cent in the women who received diet advice alone.”

According the FAO/WHO, probiotics are defined as “live microorganisms which when administered in adequate amounts confer a health benefit on the host”.

The researchers used Lactobacillus LGG (provided by Valio) and Bifidobacterium lactis (provided by Chr Hansen). Neither company provided funds for the study, with financial support coming from the Social Insurance Institution of Finland, the Academy of Finland and the Sigrid Juselius Foundation, a Finnish medical research charity.

Study details

Laitinen told attendees that 256 women were randomly divided into three groups during the first trimester of pregnancy. Two of the groups received dietary counseling consistent with current recommendations. One of those groups also received the daily probiotic capsules, while the other group received dummy capsules. The third group received placebo capsules and no dietary counseling. Supplementation continued until the women stopped exclusive breastfeeding, up to 6 months.

At the end of the study, central obesity was recorded in 18 per cent fewer women in the probiotic group than in women who received placebo plus dietary counseling, and 15 per cent fewer women in the control group.

Average body fat percentage was 28 per cent in the probiotic group, compared to 29 and 30 per cent in the diet advice only group and the control group, respectively.

Laitinen told NutraIngredients.com that future research will follow the women and their babies to see whether giving probiotics during pregnancy has any influence on health outcomes in the children.

Gut health and body weight

A breakthrough paper published in Nature in December 2006 reported that microbial populations in the gut are different between obese and lean people, and that when the obese people lost weight their microflora reverted back to that observed in a lean person, suggesting that obesity may have a microbial component.

At a scientific symposium organised by the Beneo Group last year, Dr. Kieran Touhy from the University of Reading noted that obese animals have significantly lower bifidobacteria levels than their lean counterparts, which suggests potential for prebiotic fibres since the growth of these bacteria is selectively promoted by inulin and fructooligosaccharides.

Dr. Nathalie Delzenne from the Catholic University of Louvain in Belgium and Dr. Robert Welch from the University of Ulster presented results from animal and human studies, respectively, which indicated the potential of prebiotic supplementation to regulated food intake.

A study involving scientists from Nestle, the Catholic University of Louvain, and the Institute of Molecular Medicine Rangueil in Toulouse, reported last year that direct modulation of the gut microflora using could directly affect metabolism, as well as influencing the maintenance of whole body glucose equilibrium, independent of food intake or obesity (FASEB Journal, doi:10.1096/fj.07-102723).
“The advantage of studying pregnant women to investigate the potential link between probiotics and obesity is that it allows us to see the effects not only in the women, but also in their children,” said Laitinen. “Particularly during pregnancy, the impacts of obesity can be immense, with the effects seen both in the mother and the child.
“Bacteria are passed from mother to child through the birth canal, as well as through breast milk and research indicates that early nutrition may influence the risk of obesity later in life. There is growing evidence that this approach might open a new angle on the fight against obesity, either through prevention or treatment.”

Source: European Congress on Obesity

Thursday, 7 May 2009

Kirsi Laitinen et al.

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